CBGa Cannabigerolic acid
Grades as of 9 August 2026 · check cbgatlas.com/card/cbga
Specimen
- Formula
- C₂₂H₃₂O₄
- Molar mass
- 360.49 g/mol
- Role
- Universal precursor
- Intoxicating
- No
- Evidence base
- Biosynthesis characterized · pharmacology: catalogue in progress
- CAS
- 25555-57-1
- Studies in our registry
- 4
In the family
The mother acid: heat turns it into CBG, and enzymes turn it into THCA, CBDA and CBCA.
The record registry biochemistry records
Established
- Enzymatic branching → THCA THCA synthase takes CBGA as its substrate and oxidatively cyclizes it into THCA.
- Enzymatic branching → CBDA CBDA synthase, purified and characterized from Cannabis sativa, converts the same CBGA substrate into CBDA.
- Branch specificity Structure–function analysis of the branch synthases that act on CBGA, including evidence that the enzymes are imperfectly specific, which shapes which cannabinoids a plant ends up making.
Not yet established
Pharmacology: catalogue in progress. Our registry holds no effect study for CBGa.
Cardiovascular note grade: grade: Hypothesized
CBG may influence blood pressure via α2-adrenoceptor activity; the direction and magnitude of any human effect are uncharacterized. Mechanistic plausibility only: the receptor activity has been measured in the laboratory, and no study has measured a blood-pressure effect of CBG in a person. A CBG finding, printed here because CBGa shares the family; it does not transfer to CBGa. If you take blood-pressure medication or have a cardiovascular condition, consult a clinician first.
Informational only, not medical advice. Nothing here diagnoses, treats, cures or prevents any disease. Report a safety event. Peregrine Biopharma funds the platform and holds no editorial authority.