CBN Cannabinol
Grades as of 9 August 2026 · check cbgatlas.com/card/cbn
Specimen
- Formula
- C₂₁H₂₆O₂
- Molar mass
- ≈ 310.43 g/mol
- Origin
- Oxidation of Δ9-THC / THCA — no CBN synthase exists
- Accumulates in
- Aged, oxidised or poorly stored material
- Cannabis-like effects
- Mixed and mostly not observed in people
- Evidence base
- Tested in people for sleep — primary endpoints missed
- Approved use
- None, in any jurisdiction, for any indication
- Registry status
- No graded CBN record — cited in prose
- CAS
- 521-35-7
- Studies in our registry
- 0 · catalogue in progress
In the family
What THC becomes as it ages and oxidises. No enzyme makes it; it builds up in aged, oxidised or poorly stored material.
The record cited in prose · ungraded
Established
- Chemical identity C₂₁H₂₆O₂ (≈ 310.43 g/mol).
- Formed by oxidation, with no enzyme involved Two routes lead there.
- Its level tracks age, not chemotype Oxidation is the engine, so CBN content climbs with exposure to air, light, heat and time.
Not yet established
- Any approved use as a sleep medicine Not established.
- Efficacy on a pre-specified primary endpoint Not established, though it has been tested.
- Efficacy measured objectively, by polysomnography Not established.
Cardiovascular note grade: grade: Hypothesized
CBG may influence blood pressure via α2-adrenoceptor activity; the direction and magnitude of any human effect are uncharacterized. Mechanistic plausibility only: the receptor activity has been measured in the laboratory, and no study has measured a blood-pressure effect of CBG in a person. A CBG finding, printed here because CBN shares the family; it does not transfer to CBN. If you take blood-pressure medication or have a cardiovascular condition, consult a clinician first.
Informational only, not medical advice. Nothing here diagnoses, treats, cures or prevents any disease. Report a safety event. Peregrine Biopharma funds the platform and holds no editorial authority.