Graded claim

CBG for inflammation

What does the evidence show for CBG and inflammation (colitis)?

Initial studies in animal models suggest CBG may reduce certain markers of inflammation in the colon. No controlled human trials have been completed; these findings are early-stage and not proof of benefit in humans.

grade: Lowpreclinical only
What reaching the next rung would take

Any one of these, on top of what our registry already holds:

  • one animal (preclinical) effect study from a research group not already counted here
  • one human trial of any size — including a small, short (acute / single-dose) one

The grade weighs the claim as a whole, across every study our registry holds on the question. How good any one of those papers is remains a separate matter, and you can judge each on its own terms.

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Studies behind this grade

2013

Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease

Borrelli et al. · Biochemical Pharmacology · PMID 23415610 · study type: Animal · preclinical

animal model (DNBS murine colitis) · animal

PubMed →

Registered clinical trials on this question

One trial is running now. Someone is putting the question to the test, and that alone sets it apart from the questions nobody has asked. A registration is not evidence, though, and none of the records below changes the grade above.

2024

A clinical study to assess the efficacy of cannabigerol in patients with active rheumatoid arthritis

Raphael Pharma · N/A · n=12 · running now

Rheumatoid arthritis

NCT06513507 →
2023

Efficacy and safety of hemp-derived, full-spectrum cannabigerol in adults

Formula30A LLC · N/A · n=69 · completed · no publication located

Subjective health, Inflammatory response

NCT05743985 →

Source: ClinicalTrials.gov, retrieved 2026-08-31. A completed trial marked no publication located is one our search came up empty on, and searches by trial identifier are known to miss papers. So we write “never published” only when we have positive evidence for it.

Other conditions we cover

The CBG monograph covers the compound end to end, and the gap-map charts the questions nobody has tested yet.

CBG acts on α2-adrenoceptors, which help regulate blood pressure; anyone taking cardiovascular medication should consult a clinician before using CBG products. Nothing on this page is medical advice, and no statement here is a claim that CBG treats, cures, or prevents any condition. Grades are based on the studies we had checked as of 9 August 2026. Report a safety event. Peregrine Biopharma funds the platform and holds no editorial authority.